Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes High Risk for Chronic Kidney Disease in Asian Male with Hypertension–A Meta-Regression Analysis of 98 Observational Studies
作者： Chin Lin , Hsin-Yi Yang , Chia-Chao Wu , Herng-Sheng Lee , Yuh-Feng Lin
DOI: 10.1371/JOURNAL.PONE.0087604
关键词:
摘要: Background Associations between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphisms and chronic kidney disease (CKD) have been extensively studied, with most studies reporting that individuals the D allele a higher risk. Although some factors, such as ethnicity, may moderate association ACE I/D CKD risk, gender-dependent effects on risk remain controversial.
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