摘要: OBJECTIVE: Body dysmorphic disorder, preoccupation with an imagined defect in appearance, is included DSM-III-R but has received little empirical study. The authors investigated the demographics, phenomenology, course, associated psychopathology, family history, and response to treatment a series of 30 patients disorder. METHOD: (including 12 whose was probable delusional intensity) were assessed semistructured interview Structural Clinical Interview for DSM-III-R, their histories obtained. RESULTS: 17 men 13 women reported lifetime average four bodily preoccupations, most commonly "defects" hair, nose, skin. age at onset body disorder 15 years, duration 18 years. Seventy-three percent ideas or delusions reference; 73%, excessive mirror checking; 63%, attempts camouflage "deformities." As result symptoms, 97% avoided usual social occupational activities, 30% had been housebound, 17% made suicide attempts. Ninety-three diagnosis major mood disorder; 33%, psychotic anxiety generally responded poorly surgical, dermatologic, dental treatments adequate trials psychotropic medications, exception fluoxetine clomipramine (to which more than half complete partial response). CONCLUSIONS: This often secret, chronic can cause considerable distress impairment, may be related obsessive-compulsive respond serotonin reuptake-blocking antidepressants. Language: en