Carcinomes des voies aérodigestives supérieures: nouvelles approches en radiothérapie
作者： R. Mazeron , J. Bourhis
DOI: 10.1007/S10269-008-0831-5
关键词:
摘要: La radiotherapie des cancers epidermoides de la tete et du cou necessite delivrer doses importantes (> 50 Gy) pour tumeurs proches d’organes a risque comme le larynx, moelle epiniere ou les glandes parotides. Malgre l’apport associations radiotherapie-chimiotherapie progres chirurgie reparatrice, pronostic stades localement avances reste relativement mediocre avec survies estimees 30 40 % cinq ans, justifiant nouvel-les approches therapeutiques qui s’articulent autour deux objectifs: ameliorer controle locoregional assurer une meilleure protection tissus sains. Pour cela, axes principaux sont etudies: balistique developpement haute precision radiobiologie (fractionnement, radiosensibilisants radioprotecteurs, association aux therapies moleculaires ciblees).
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