Translating rodent behavioral repertoire to zebrafish (Danio rerio): relevance for stress research.

摘要: Abstract The current study provides a detailed description of the pattern exploratory behaviors encountered in adult zebrafish when exposed to novel/unfamiliar environment using light/dark box and open field tests. We also document impact an acute stressor (restraint stress) given just prior onset behavioral testing. report following main findings: (1) display anxiety-like including dark-avoidance (in test) thigmotaxis test), (2) upon exposure novel (first 2 min), place preference for outer zone testing apparatus where they seek escape via transparent wall, exhibit high locomotor activity accompanied by swimming speed, (3) thigmotaxis, hyperactivity, speed habituate (decrease) over time, (4) history stress attenuates natural tendency engage behavior reduces attempts greatly increased hyperactivity speed. Stress-induced patterns normalize levels comparable that non-stressed controls end 5-min test session. Taken together, these findings suggest can elicit such as affects exploration, defensive behaviors, coping strategies These are consistent with previous rodents support usefulness paradigms zebrafish.