Racial Disparities in Incidence of Young-Onset Colorectal Cancer and Patient Survival.

作者: Caitlin C. Murphy , Kristin Wallace , Robert S. Sandler , John A. Baron

DOI: 10.1053/J.GASTRO.2018.11.060

关键词:

摘要: Background & Aims Increasing rates of young-onset colorectal cancer (CRC) have attracted substantial research and media attention, but we know little about racial disparities among younger adults with CRC. We examined in CRC by comparing incidence relative survival ( Methods Using data from the Surveillance, Epidemiology, End Results program registries, estimated (per 100,000 persons 20–49 years old) 1992 through 2014 for different periods (1992–1996 vs 2010–2014) races (white black). Relative was calculated as ratio observed to expected a comparable cancer-free population. From 1992–1996 2010–2014, increased 7.5 11.0 per white individuals 11.7 12.7 black individuals. The increase rectal larger whites (from 2.7 4.5 100,000) than blacks 3.4 4.0 100,000); 2010–2014 period, had similar cancer. Compared whites, smaller increases proximal colon 55.3% 70.8%). Conclusion In an analysis database, found patient minimal difference Well-documented recent largely been due cancer, especially whites.

参考文章(60)
Blase N. Polite, Amy Sing, Daniel J. Sargent, Axel Grothey, Jordan Berlin, Mark Kozloff, Shibao Feng, Exploring racial differences in outcome and treatment for metastatic colorectal cancer Cancer. ,vol. 118, pp. 1083- 1090 ,(2012) , 10.1002/CNCR.26394
Frank A. Sinicrope, Nathan R. Foster, Greg Yothers, Al Benson, Jean Francois Seitz, Roberto Labianca, Richard M. Goldberg, Aimery DeGramont, Michael J. O'Connell, Daniel J. Sargent, , Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy Cancer. ,vol. 119, pp. 1528- 1536 ,(2013) , 10.1002/CNCR.27938
S. A. Suttie, I. Shaikh, R Mullen, A. I. Amin, T. Daniel, S. Yalamarthi, Outcome of right- and left-sided colonic and rectal cancer following surgical resection. Colorectal Disease. ,vol. 13, pp. 884- 889 ,(2011) , 10.1111/J.1463-1318.2010.02356.X
Vincent K. Dik, Martijn G. H. van Oijen, Hugo M. Smeets, Peter D. Siersema, Frequent Use of Antibiotics Is Associated with Colorectal Cancer Risk: Results of a Nested Case-Control Study Digestive Diseases and Sciences. ,vol. 61, pp. 255- 264 ,(2016) , 10.1007/S10620-015-3828-0
Caitlin C. Murphy, Linda C. Harlan, Jennifer L. Lund, Charles F. Lynch, Ann M. Geiger, Patterns of Colorectal Cancer Care in the United States: 1990–2010 Journal of the National Cancer Institute. ,vol. 107, ,(2015) , 10.1093/JNCI/DJV198
Harry H. Yoon, Qian Shi, Steven R. Alberts, Richard M. Goldberg, Stephen N. Thibodeau, Daniel J. Sargent, Frank A. Sinicrope, , Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients Journal of the National Cancer Institute. ,vol. 107, ,(2015) , 10.1093/JNCI/DJV186
Nestor F. Esnaola, Marvella E. Ford, Racial differences and disparities in cancer care and outcomes: where's the rub? Surgical Oncology Clinics of North America. ,vol. 21, pp. 417- 437 ,(2012) , 10.1016/J.SOC.2012.03.012
A. B. Mariotto, A.-M. Noone, N. Howlader, H. Cho, G. E. Keel, J. Garshell, S. Woloshin, L. M. Schwartz, Cancer survival: an overview of measures, uses, and interpretation. Journal of The National Cancer Institute Monographs. ,vol. 2014, pp. 145- 186 ,(2014) , 10.1093/JNCIMONOGRAPHS/LGU024
Amanda I. Phipps, Noralane M. Lindor, Mark A. Jenkins, John A. Baron, Aung Ko Win, Steven Gallinger, Robert Gryfe, Polly A. Newcomb, Colon and Rectal Cancer Survival by Tumor Location and Microsatellite Instability Diseases of the Colon & Rectum. ,vol. 56, pp. 937- 944 ,(2013) , 10.1097/DCR.0B013E31828F9A57
Jessica B O'Connell, Melinda A Maggard, Edward H Livingston, Cifford K Yo, Colorectal cancer in the young. American Journal of Surgery. ,vol. 187, pp. 343- 348 ,(2004) , 10.1016/J.AMJSURG.2003.12.020