Prognostic and predictive biomarkers in prostate cancer.

摘要: Prostate cancer (PCa) is one of the leading causes death among males, especially in more developed countries. Diagnosis often achieved at an early stage disease with prostate biopsy, following a screening test showing elevated serum levels prostate-specific antigen or positive digital rectal examination. Early detection PCa has led to substantial decline number metastatic patients. However, proved be double-edged sword so far, as it also accounts for overdiagnosis. Due variability features, accurate prognosis patients very important determining treatment options. Therefore, this review focuses on most promising prognostic and predictive biomarkers PCa, which are likely play pivotal role, alone panels, personalized medicine era that recently emerged.