Turnover of circulating hematopoietic stem cells

摘要: Short-term parabiosis of male and female CBA/CaJ mice was used to investigate the turnover circulating hematopoietic stem cells. The exchange subsequent disappearance donor cells were monitored by spleen colony assay chromosome analysis individual colonies. results revealed an exponential pluripotent from blood with a characteristic half time 1.7 h. Blood-borne shown be equilibrated subpopulation marrow exhibiting 9.5 Splenectomy did not change apparent rate cell removal blood.