The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics.
作者： J. A. Blake , C. J. Bult , J. A. Kadin , J. E. Richardson , J. T. Eppig
DOI: 10.1093/NAR/GKQ1008
关键词:
摘要: The Mouse Genome Database (MGD) is the community model organism database for laboratory mouse and authoritative source phenotype functional annotations of genes. MGD includes a complete catalog genes genome features with integrated access to genetic, genomic phenotypic information, all serving further use as system studying human biology disease. major component Informatics (MGI, http://www.informatics.jax.org/) resource. contains standardized descriptions phenotypes, associations between models genetic diseases, extensive integration DNA protein sequence data, normalized representation variant information. Data are obtained via manual curation biomedical literature, direct contributions from individual investigators downloads informatics resource centers. collaborates bioinformatics on development ontologies such Gene Ontology (GO) Mammalian Phenotype (MP) Ontology. Major improvements include comprehensive update maps, implementation new classification terms features, recombinase (cre) portal inclusion alleles generated by International Knockout Consortium (IKMC).
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