endo-Functionalized molecular tubes: selective encapsulation of neutral molecules in non-polar media

作者: Guobao Huang , Arto Valkonen , Kari Rissanen , Wei Jiang

DOI: 10.1039/C6CC00349D

关键词:

摘要: Four endo-functionalized molecular tubes with urea/thiourea groups in the deep cavities have been synthesized, and their binding ability to neutral molecules studied. Very high affinity selectivity achieved, which are rationalized by invoking shape electrostatic complementarity dipole alignment.

参考文章(28)
Fei Jia, Zhenfeng He, Liu-Pan Yang, Zhi-Sheng Pan, Min Yi, Ren-Wang Jiang, Wei Jiang, Oxatub[4]arene: a smart macrocyclic receptor with multiple interconvertible cavities Chemical Science. ,vol. 6, pp. 6731- 6738 ,(2015) , 10.1039/C5SC03251B
Guobao Huang, Zhenfeng He, Chen-Xi Cai, Fangfang Pan, Dingqiao Yang, Kari Rissanen, Wei Jiang, Bis-urea macrocycles with a deep cavity Chemical Communications. ,vol. 51, pp. 15490- 15493 ,(2015) , 10.1039/C5CC06768E
Jianyu Xin, Zhizhang Guo, Xingyu Chen, Wenfeng Jiang, Jianshu Li, Maolin Li, Study of branched cationic β-cyclodextrin polymer/indomethacin complex and its release profile from alginate hydrogel International Journal of Pharmaceutics. ,vol. 386, pp. 221- 228 ,(2010) , 10.1016/J.IJPHARM.2009.11.024
Salvatore Zarra, Daniel M. Wood, Derrick A. Roberts, Jonathan R. Nitschke, Molecular containers in complex chemical systems Chemical Society Reviews. ,vol. 44, pp. 419- 432 ,(2015) , 10.1039/C4CS00165F
Zhenhui Qi, Thomas Heinrich, Suresh Moorthy, Christoph A. Schalley, Gas-phase chemistry of molecular containers Chemical Society Reviews. ,vol. 44, pp. 515- 531 ,(2015) , 10.1039/C4CS00167B
Liang Zhao, Koushik Ghosh, Yao-Rong Zheng, Peter J. Stang, Construction of Endo-Functionalized Two Dimensional Metallacycles via Coordination-Driven Self-Assembly Journal of Organic Chemistry. ,vol. 74, pp. 8516- 8521 ,(2009) , 10.1021/JO9019607
Louis Adriaenssens, Pablo Ballester, Hydrogen bonded supramolecular capsules with functionalized interiors: the controlled orientation of included guests Chemical Society Reviews. ,vol. 42, pp. 3261- 3277 ,(2013) , 10.1039/C2CS35461F
B. W. Purse, J. Rebek, Functional cavitands: chemical reactivity in structured environments. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 10777- 10782 ,(2005) , 10.1073/PNAS.0501731102
Sandro Mecozzi, Julius Rebek, Jr., The 55 % Solution: A Formula for Molecular Recognition in the Liquid State Chemistry: A European Journal. ,vol. 4, pp. 1016- 1022 ,(1998) , 10.1002/(SICI)1521-3765(19980615)4:6<1016::AID-CHEM1016>3.0.CO;2-B