Microbiota of health, gingivitis, and initial periodontitis.

摘要: This study compared the subgingival microbiota in periodontal health, gingivitis and initial periodontitis using predominant culture a DNA probe, checkerboard hybridization method. 56 healthy adult subjects with minimal attachment loss were clinically monitored at 3-month intervals for 12 months. More sites demonstrated small increments of than gain over monitoring period. Sites, from 17 subjects, showing > or = 1.5 mm during sampled as active lesions microbial analysis. Twelve interproximal lesions, 5 had buccal (recession). Cultural studies identified Bacteroides forsythus, Campylobacter rectus, Selenomonas noxia species associated (9 subjects), whereas Actinomyces naeslundii, Streptococcus oralis, dominant colonizing sites. A. gracilis, B. forsythus (at lower levels sites) cultured (10 subjects). Health-associated subjects) included gerencseriae. probe data higher mean C. rectus (7 to inactive Porphyromonas gingivalis Actinobacillus actinomycetemcomitans detected infrequently. Cluster analysis cultural grouped 8/9 one subcluster characterized by mostly gram-negative microbiota, including rectus. The suggest that S. major characterizing converting health disease. differences location suggested different mechanisms may be involved increased loss.