Feasibility and utility of transcutaneous spinal cord stimulation combined with walking-based therapy for people with motor incomplete spinal cord injury.

摘要: Study design Prospective case series. Objectives To evaluate the feasibility and preliminary efficacy of combining transcutaneous spinal cord stimulation (TSCS) with walking-based physical therapy. Setting Hospital-based outpatient center in Maryland, United States. Methods Ten individuals chronic (>1 year) motor incomplete injury (iSCI) completed 23 sessions 2-h therapy over 8 weeks. TSCS was delivered for first 30 min each session using a clinically available device adjustable current. assess intervention, we tracked pain, adverse events, participant retention. Preliminary assessed by evaluating changes walking speed, endurance, quality following intervention select functional outcome measures (10-m walk test (10MWT), 6-min (6MWT), timed up go, index II). Results We found that combined feasible an clinical setting. Participants tolerated well, no reports significant events or other issues (e.g., skin irritation pain disrupted training). None participants elected to discontinue study. also showed improvements measure function intervention. Changes as measured 10MWT (0.56 ± 0.29 m/s 0.72 0.36 m/s), exceeded minimal important difference iSCI. 6MWT (149.88 99.87 m 194.53 106.56 m), detectable change Conclusions These results indicate is may be useful adjunct adults