Pathology of pulmonary endocrine neoplasms

摘要: This chapter discusses the pathology of endocrine tumors lung, emphasizing their morphology and differential diagnosis. Histologically, carcinoid are characterized by a well developed architecture. The most common pattern growth is insular, with relatively solid masses cells neatly separated fibrovascular stroma Cigarette smoking significant etiological agent in causation small cell carcinoma. However, there clear dose-response relationship it rare nonsmokers. Distinguishing between different pulmonary can be difficult—a problem to all attempts categorize, as distinct entities, lesions constituting continuous spectrum. Certain features lung shared tumorlets they considered continuum. Tumorlets peripheral might result from same abnormal stimulus or latter induce secondary proliferation cells, some way.