A Possible Subclass of the Hereditary Persistence of Fetal Hemoglobin

作者: T. H. J. HUISMAN , W. A. SCHROEDER , H. R. ADAMS , J. ROGER SHELTON , JOAN BALOG SHELTON

DOI: 10.1182/BLOOD.V36.1.1.1

关键词:

摘要: Four individuals in two generations of a Caucasian family have about 5 per cent Hb-F which the sole type γ chain is that with alanine position 136. It suggested these heterozygotes may constitute subclass hereditary persistence fetal hemoglobin.

参考文章(13)
PHAEDON FESSAS, GEORGE STAMATOYANNOPOULOS, HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN IN GREECE. A STUDY AND A COMPARISON. Blood. ,vol. 24, pp. 223- 240 ,(1964) , 10.1182/BLOOD.V24.3.223.223
K. BETKE, H. R. MARTI, I. SCHLICHT, Estimation of Small Percentages of Fœtal Hæmoglobin Nature. ,vol. 184, pp. 1877- 1878 ,(1959) , 10.1038/1841877A0
Titus H.J. Huisman, Andrée M. Dozy, Studies on the heterogeneity of hemoglobin Journal of Chromatography A. ,vol. 19, pp. 160- 169 ,(1965) , 10.1016/S0021-9673(01)99434-8
C. LOCKARD CONLEY, DAVID J. WEATHERALL, STUART N. RICHARDSON, MARGUERITE K. SHEPARD, SAMUEL CHARACHE, Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore. Blood. ,vol. 21, pp. 261- 281 ,(1963) , 10.1182/BLOOD.V21.3.261.261
Titus H.J. Huisman, NORMAL AND ABNORMAL HUMAN HEMOGLOBINS. Advances in Clinical Chemistry. ,vol. 6, pp. 231- 361 ,(1963) , 10.1016/S0065-2423(08)60160-2
W. E. Nance, Genetic Control of Hemoglobin Synthesis Science. ,vol. 141, pp. 123- 130 ,(1963) , 10.1126/SCIENCE.141.3576.123
WILLIAM SIEGEL, An Adult Homozygous for Persistent Fetal Hemoglobin Annals of Internal Medicine. ,vol. 72, pp. 533- 536 ,(1970) , 10.7326/0003-4819-72-4-533
W. A. Schroeder, T. H. Huisman, J. R. Shelton, J. B. Shelton, E. F. Kleihauer, A. M. Dozy, B. Robberson, Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 60, pp. 537- 544 ,(1968) , 10.1073/PNAS.60.2.537