Impact of food and different meal types on the pharmacokinetics of rilpivirine.

作者: Herta M. Crauwels , Rolf P.G. van Heeswijk , Annemie Buelens , Marita Stevens , Katia Boven

DOI: 10.1002/JCPH.107

关键词:

摘要: … soluble compounds such as rilpivirine. An early food interaction study showed that the relative oral bioavailability of rilpivirine … were always instructed to take rilpivirine with a meal, …

参考文章(18)
Aimee Wilkin, Anton L. Pozniak, Javier Morales-Ramirez, Sergio H. Lupo, Mario Santoscoy, Beatriz Grinsztejn, Kiat Ruxrungtham, Laurence T. Rimsky, Simon Vanveggel, Katia Boven, on behalf of the TMC278-C204, Long-term efficacy, safety, and tolerability of rilpivirine (RPV, TMC278) in HIV type 1-infected antiretroviral-naive patients: week 192 results from a phase IIb randomized trial. AIDS Research and Human Retroviruses. ,vol. 28, pp. 437- 446 ,(2011) , 10.1089/AID.2011.0050
Monika Schöller-Gyüre, Marta Boffito, Anton L Pozniak, Ruud Leemans, Thomas N Kakuda, Brian Woodfall, Veerle Vyncke, Monika Peeters, Kati Vandermeulen, Richard M. W Hoetelmans, Effects of Different Meal Compositions and Fasted State on the Oral Bioavailability of Etravirine Pharmacotherapy. ,vol. 28, pp. 1215- 1222 ,(2008) , 10.1592/PHCO.28.10.1215
Gene D Morse, Margaret A Fischl, Mark J Shelton, Steve R Cox, Leslie Thompson, Andrew A Della-Coletta, William W Freimuth, Effect of Food on the Steady-State Pharmacokinetics of Delavirdine in Patients with HIV Infection. Clinical Drug Investigation. ,vol. 23, pp. 255- 261 ,(2003) , 10.2165/00044011-200323040-00005
Xiaohong Cai, David J.W. Grant, Timothy S. Wiedmann, Analysis of the Solubilization of Steroids by Bile Salt Micelles Journal of Pharmaceutical Sciences. ,vol. 86, pp. 372- 377 ,(1997) , 10.1021/JS9602148
Bertil Abrahamsson, Tamsin Albery, Anna Eriksson, Ingrid Gustafsson, Marie Sjöberg, Food effects on tablet disintegration. European Journal of Pharmaceutical Sciences. ,vol. 22, pp. 165- 172 ,(2004) , 10.1016/J.EJPS.2004.03.004
David Fleisher, Cheng Li, Yuji Zhou, LiHeng Pao, Aziz Karim, Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications. Clinical Pharmacokinectics. ,vol. 36, pp. 233- 254 ,(1999) , 10.2165/00003088-199936030-00004
Calvin J. Cohen, Jean-Michel Molina, Isabel Cassetti, Ploenchan Chetchotisakd, Adriano Lazzarin, Chloe Orkin, Frank Rhame, Hans-Jürgen Stellbrink, Taisheng Li, Herta Crauwels, Laurence Rimsky, Simon Vanveggel, Peter Williams, Katia Boven, Week 96 efficacy and safety of rilpivirine in treatment-naive, HIV-1 patients in two Phase III randomized trials. AIDS. ,vol. 27, pp. 939- 950 ,(2013) , 10.1097/QAD.0B013E32835CEE6E
Anton L Pozniak, Javier Morales-Ramirez, Elly Katabira, Dewald Steyn, Sergio H Lupo, Mario Santoscoy, Beatriz Grinsztejn, Kiat Ruxrungtham, Laurence T Rimsky, Simon Vanveggel, Katia Boven, TMC278-C204 study group, Efficacy and safety of TMC278 in antiretroviral-naive HIV-1 patients: week 96 results of a phase IIb randomized trial. AIDS. ,vol. 24, pp. 55- 65 ,(2010) , 10.1097/QAD.0B013E32833032ED
Laura Dickinson, Saye Khoo, David Back, Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons. Current Opinion in Hiv and Aids. ,vol. 3, pp. 296- 305 ,(2008) , 10.1097/COH.0B013E3282F82BF1
Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P de Béthune, Monika Peeters, Brian Woodfall, Short-term antiviral activity of TMC278 – a novel NNRTI – in treatment-naive HIV-1-infected subjects AIDS. ,vol. 20, pp. 1721- 1726 ,(2006) , 10.1097/01.AIDS.0000242818.65215.BD