Intestinal transport of amino acids studied in vitro with l-[131I]monoiodotyrosine

作者: Daniel Nathans , Donald F. Tapley , Joan E. Ross

DOI: 10.1016/0006-3002(60)90010-X

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摘要: Abstract The transport of l -[131I]monoiodotyrosine by everted sacs small intestine is dependent on active accumulation this amino acid in the gut wall, terminal ileum being most segment. Its stimulated glucose, which depresses efflux monoiodotyrosine from mucosal surface intestine. Certain aminoacids and potassium ion competitively inhibit moniodotyrosine transport. α-amino acids -configuration with a free group long non-polar side-chain are effective inhibitors.

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