The Cell Cycle, Cell Lineage, and Neuronal Specificity

摘要: The first principle of neuronal differentiation is the generation cellular diversity which, at least quantitatively, matches that found in entire remainder embryo. More importantly, it characteristic differences among neurons (rather than properties which all share to exclusion non-neural cells) enables them associate selectively and assemble synaptic circuits are substrates macroscopic brain function. Neuronal must be viewed, therefore, not simply as a process by “zygote” cells generate “nerve” cells, but rather systematic derivation from zygote cell population with characteristically diverse specificities. This review considers some aspects specificity possible role(s) cycle lineage differentiation.