BONE TISSUE REGENERATING PEPTIDES

摘要: The present invention provides a recombinant or synthetic fusion polypeptide comprising peptide component with bone tissue renerating activity, linker and an antimicrobial competence stimulating activity. peptide, which enhances osteogenic cell binding, is useful for repairing dental bony defects such as those caused by loss resulting from moderate to severe periodontitis, augmenting of the alveolar ridge, filling tooth extraction sites, sinus elevation grafting. repair material includes porous, resorbable particulate that derived bone-like hydroxyapatite hydroxylapatite and/or carrier high molecular weight polysaccharides. Furthermore, alone this treatment fractures, filler in deficient sites bone, inhibition decrease substance related osteoporosis, also prevention fractures associated osteoporosis rheumatoid arthritis. can be combined bone-compatible matrix facilitate slow release site provide structure developing bone.