The Cancer Spectrum Related to Hereditary and Familial Breast and Ovarian Cancers

作者: Matilde Pensabene , Rosaria Gesuita , Ida Capuano , Caterina Condello , Ilaria Spagnoletti

DOI: 10.1007/978-88-470-1095-6_10

关键词:

摘要: Multiple factors are associated with an increased risk of developing breast cancer, including age, family history, exposure to reproductive hormones, dietary factors, benign diseases, and environmental factors. Recently, increasing interest has been devoted the interaction between genetic Family history recognized as important factor for cancer. Individuals a first-degree member affected cancer have relative 2.1 (95% CI = 2.0–2.2). Moreover, varies age at which was diagnosed, number unaffected members and, finally, closeness relationship.

参考文章(32)
Laura Cortesi, Daniela Turchetti, Isabella Marchi, Antonella Fracca, Barbara Canossi, Rachele Battista, Silvia Ruscelli, Anna Rita Pecchi, Pietro Torricelli, Massimo Federico, Breast cancer screening in women at increased risk according to different family histories: an update of the Modena Study Group experience BMC Cancer. ,vol. 6, pp. 210- 210 ,(2006) , 10.1186/1471-2407-6-210
Gad Rennert, Shantih Bisland-Naggan, Ofra Barnett-Griness, Naomi Bar-Joseph, Shiyu Zhang, Hedy S. Rennert, Steven A. Narod, Clinical outcomes of breast cancer in carriers of BRCA1 and BRCA2 mutations. The New England Journal of Medicine. ,vol. 357, pp. 115- 123 ,(2007) , 10.1056/NEJMOA070608
C. Condello, R. Gesuita, M. Pensabene, I. Spagnoletti, I. Capuano, C. Baldi, F. Carle, A. Contegiacomo, Distress and Family Functioning in Oncogenetic Counselling for Hereditary and Familial Breast and/or Ovarian Cancers Journal of Genetic Counseling. ,vol. 16, pp. 625- 634 ,(2007) , 10.1007/S10897-007-9102-7
P. Hopwood, C.J. van Asperen, G. Borreani, P. Bourret, M. Decruyenaere, S. Dishon, F. Eisinger, D.G.R. Evans, G. Evers-Kiebooms, L. Gangeri, L. Hagoel, E. Legius, I. Nippert, G. Rennert, B. Schlegelberger, C. Sevilla, H. Sobol, A. Tibben, M. Welkenhuysen, C. Julian-Reynier, Cancer genetics service provision: a comparison of seven European centres. Community Genetics. ,vol. 6, pp. 192- 205 ,(2003) , 10.1159/000079381
Mark Robson, Kenneth Offit, Management of an Inherited Predisposition to Breast Cancer New England Journal of Medicine. ,vol. 357, pp. 154- 162 ,(2007) , 10.1056/NEJMCP071286
Deborah Thompson, Douglas F Easton, Cancer Incidence in BRCA1 Mutation Carriers Journal of the National Cancer Institute. ,vol. 94, pp. 1358- 1365 ,(2002) , 10.1093/JNCI/94.18.1358
J. E. Garber, S. Syngal, One Less Thing to Worry About: The Shrinking Spectrum of Tumors in BRCA Founder Mutation Carriers Journal of the National Cancer Institute. ,vol. 96, pp. 2- 3 ,(2004) , 10.1093/JNCI/DJH021
B. L. Niell, G. Rennert, J. D. Bonner, R. Almog, L. P. Tomsho, S. B. Gruber, BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. Journal of the National Cancer Institute. ,vol. 96, pp. 15- 21 ,(2004) , 10.1093/JNCI/DJH008
Dewajani Purnomosari, Gerard Pals, Artanto Wahyono, Teguh Aryandono, Tjakra W. Manuaba, Samuel J. Haryono, Paul J. van Diest, BRCA1 and BRCA2 germline mutation analysis in the Indonesian population. Breast Cancer Research and Treatment. ,vol. 106, pp. 297- 304 ,(2007) , 10.1007/S10549-006-9493-4