The use of Peritoneal Mesothelium as a Potential Source of Adult Stem Cells

摘要: At the dawn of 21st century, classical curative medicine is being challenged by fact that efforts to fight and prevent not a few diseases, are in many circumstances, beyond power pharmacological armamentarium medical profession. On other hand, replacement lost function mechanical or biophysical devices, even organ transplantation, prolongs life but generally derives new and, at times, unsolvable problems. Regenerative therapy using stem cells began revolutionary trend may well change both therapeutic approach diseases resulting from failing organs, as fate quality millions patients. The presence pluripotent mesenchymal mesothelial monolayer submesothelial connective tissue raises possibility peritoneal mesothelium regenerative therapies. This perception problem also based on observations made humans laboratory animals showing bone, bone marrow, cartilaginous tissue, glomerular-like structures creation blood conducts, pathological situations (mesothelioma, sclerosing peritonitis), after vivo ex experimental interventions. main concept emerging this information endowed with such degree plasticity that, if placed appropriate micro-environment, they have remarkable potential generate mesenchymal-derived cell lines. Intensive research required define best environmental conditions take advantage make an actual option be applied medicine.