Dopaminergic genotype biases spatial attention in healthy children

摘要: In everyday life, our sensory system is bombarded with visual input and we rely upon attention to select only those inputs that are relevant behavioural goals. Typically, humans can shift their from one field the other little cost perception. cases of 'unilateral neglect', however, there a persistent bias spatial towards same side as damaged cerebral hemisphere. We used orienting task examine influence functional polymorphisms dopamine transporter gene (DAT1) on individual differences in normally developing children. DAT1 genotype significantly influenced bias. Healthy children who were homozygous for alleles expression transporters brain displayed inattention left-sided stimuli, whereas heterozygotes did not. Our data provide first evidence healthy individuals genetically mediated related signalling.