Constructing Multiply Substituted Arenes Using Sequential Palladium(II)‐Catalyzed C ? H Olefination
作者： Keary M. Engle , Dong-Hui Wang , Jin-Quan Yu
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摘要: Complementary catalytic systems have been developed in which the reactivity/selectivity balance Pd(II)-catalyzed ortho-C–H olefination can be modulated through ligand control. This allows for sequential C–H functionalization rapid preparation of 1,2,3-trisubstituted arenes. Additionally, a rare example iterative activation, newly installed functional group directs subsequent activation has demonstrated.
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