作者: Chisato Makino
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摘要: The present invention provides a method for producing pharmaceutical preparation having an improved solubility, which comprises the steps of forming micelle by dissolving poorly-soluble drug ability to form into water; and fixing structure is formed with drug, using compound(s) fixes structure. This production preferably further step adjusting pH back neutral and/or cooling down temperature room after subject above such as those in water only when heated presence acid(s) or alkali(s). According this method, it can produce makes possible accomplish improvement oral absorbability drug(s).