The nonulosaminic acids; neuraminic acids and related compounds (sialic acids).

摘要: Publisher Summary The members of the group, neuraminic acid and its higher acylated derivatives, so-called “sialic acids,” are found widely distributed throughout animal kingdom in mucopolysaccharides, mucoproteins, lipopolysaccharides (mucolipids)-very often association with D-glucosamine D-galactosamine. Generically, they may be designated nonulosaminic acids; or, more precisely, amino-carboxy-deoxynonuloses, since possess a keto group addition to an amino carboxyl group. name “neuraminic acid” was first given monomethoxy compound, isolated after methanolysis gangliosides, then subsequently transferred methoxyl-free, parent acid. has been several acids from submaxillary although chemical composition these varies species source. Like other naturally occurring sugars, not present Nature free-state any appreciable extent. They found, together hexoses, combined mucolipids mucoproteins sources. These mucosubstances also contain content