A mycoplasma high-affinity transport system and the in vitro invasiveness of mouse sarcoma cells.

摘要: Abstract FS9 mouse sarcoma cells were previously shown to be highly invasive when confronted with chicken heart fibroblasts using Abercrombie's explant technique. This invasion could inhibited by addition the assay of Fab fragments a monoclonal antibody directed against p37, protein associated surface FS9 cells. We have cloned and sequenced gene for p37. show that it originates from Mycoplasma hyorhinis UGA is tryptophan codon in this organism. present evidence p37 part an operon encoding two additional proteins which are similar components periplasmic binding-protein-dependent transport systems Gram-negative bacteria, we suggest homologous, high-affinity system M. hyorhinis, Gram-positive bacterium. discuss influence on contact inhibition locomotion mammalian