Entorhinal cortex grid cells can map to hippocampal place cells by competitive learning.

摘要: ‘Grid cells’ in the dorsocaudal medial entorhinal cortex (dMEC) are activated when a rat is located at any of vertices grid equilateral triangles covering environment. dMEC cells have different frequencies and phase offsets. However, dentate gyrus (DG) hippocampal area CA3 rodent typically display place fields, where individual active over only single portion space. In model hippocampus, we shown that connectivity from to granule could allow operate as competitive network recode their inputs produce sparse orthogonal representations, this includes spatial pattern separation. paper show same computational hypothesis can account for mapping EC cells. We learning an important part way which be achieved. further i...