Palmar and axillary hyperhidrosis treated with botulinum toxin: one-year clinical follow-up.

摘要: Focal hyperhidrosis is a common and sometimes handicapping condition for which the presently most effective treatment, sympathectomy, often leads to irreversible side-effects. We aimed study effectiveness tolerability of an alternative treatment with botulinum toxin injections over period one year this condition. Twenty-eight patients palmar (n = 19) and/or axillary 13) were treated intracutaneous (Botox(R)) 2 U/4 cm2. Sweat function was studied clinically by objective measurements after side. Treated untreated sides, pre- post-treatment skin areas compared. Subjective evaluation performed side 2-5 months both sides. Duration effect controlled one-year follow-up. Sweating disappeared in eight out 13 five 19 hyperhidrosis, reduced markedly another 10 patients. Two-thirds those hand sweat noticed slight transient reduction power finger grip. No side-effects hyperhidrosis. find technique safe effective, due relatively long duration should be recommended before sympathectomy focal