Hepatitis virus: effect of heat on the infectivity and antigenicity of the MS-1 and MS-2 strains.

作者: S. Krugman , J. P. Giles , J. Hammond

DOI: 10.1093/INFDIS/122.5.432

关键词:

摘要: Studies on the natural history and prevention of viral hepatitis have been in progress at Willowbrook State School since 1956 [1-5]. The background for this investigation was described detail a recent publication [5]. During course these studies, 2 types were identified; one designated MS-1 other MS-2. type resembled classical hepatitis, A or infectious (IH). MS-2 B serum (SH). Availability separate pools containing strains virus provided pedigreed materials study IH SH viruses. Previous experience revealed that both viruses infective after exposure to temperature 56 C 30 min [1, 6]. present undertaken evaluate effect boiling (98 1 min) infectivity immunogenic capacity pools.

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