Bimodal biophotonic imaging of the structure-function relationship in cardiac tissue
作者： William J. Hucker , Crystal M. Ripplinger , Christine P. Fleming , Vadim V. Fedorov , Andrew M. Rollins
DOI: 10.1117/1.2975826
关键词:
摘要: The development of systems physiology is hampered by the limited ability to relate tissue structure and function in intact organs vivo or vitro. Here, we show application a bimodal biopho- tonic imaging approach that employs optical coherence tomography fluorescent investigate structure-function relation- ship at level heart. Reconstruction cardiac excita- tion was depth penetration 2m min atrial tissue, 1m ventricular myo- cardium. subcellular resolution clearly demonstrated microscopic fiber orientation governs pattern wave propagation functionally characterized rabbit si- noatrial atrioventricular nodal preparations revealed struc- tural heterogeneities contributing arrhythmias. combination this biophotonic with his- tology and/or immunohistochemistry can span multiple scales res- olution for investigation molecular structural determi- nants physiology. © 2008 Society Photo-Optical Instrumentation
harvard.edu
columbia.edu
elsevier.com
sci-hub.se 参考文章(26)
Sophie J. Bakri, Arun D. Singh, Careen Y. Lowder, Maria Regina Chalita, Yan Li, Joseph A. Izatt, Andrew M. Rollins, David Huang, Imaging of iris lesions with high-speed optical coherence tomography. Ophthalmic Surgery Lasers & Imaging. ,vol. 38, pp. 27- 34 ,(2007) , 10.3928/15428877-20070101-04
Handbook of optical coherence tomography Published in <b>2002</b> in New York by Marcel Dekker. ,(2001) , 10.1201/B14024
Crystal M. Ripplinger, Valentin I. Krinsky, Vladimir P. Nikolski, Igor R. Efimov, Mechanisms of unpinning and termination of ventricular tachycardia American Journal of Physiology-heart and Circulatory Physiology. ,vol. 291, ,(2006) , 10.1152/AJPHEART.01300.2005
Michael W. Jenkins, Osman Q. Chughtai, Ajay N. Basavanhally, Michiko Watanabe, Andrew M. Rollins, In vivo gated 4D imaging of the embryonic heart using optical coherence tomography. Journal of Biomedical Optics. ,vol. 12, pp. 030505- ,(2007) , 10.1117/1.2747208
Nicholas S. Peters, James Coromilas, Nicholas J. Severs, Andrew L. Wit, Disturbed Connexin43 Gap Junction Distribution Correlates With the Location of Reentrant Circuits in the Epicardial Border Zone of Healing Canine Infarcts That Cause Ventricular Tachycardia Circulation. ,vol. 95, pp. 988- 996 ,(1997) , 10.1161/01.CIR.95.4.988
Vladimir G. Fast, Simultaneous optical imaging of membrane potential and intracellular calcium Journal of Electrocardiology. ,vol. 38, pp. 107- 112 ,(2005) , 10.1016/J.JELECTROCARD.2005.06.023
William J. Karlon, James W. Covell, Andrew D. Mcculloch, John J. Hunter, Jeffrey H. Omens, Automated measurement of myofiber disarray in transgenic mice with ventricular expression ofras The Anatomical Record. ,vol. 252, pp. 612- 625 ,(1998) , 10.1002/(SICI)1097-0185(199812)252:4<612::AID-AR12>3.0.CO;2-1
M VALDERRABANO, Influence of anisotropic conduction properties in the propagation of the cardiac action potential Progress in Biophysics & Molecular Biology. ,vol. 94, pp. 144- 168 ,(2007) , 10.1016/J.PBIOMOLBIO.2007.03.014
William T. Baxter, Sergey F. Mironov, Alexey V. Zaitsev, José Jalife, Arkady M. Pertsov, Visualizing Excitation Waves inside Cardiac Muscle Using Transillumination Biophysical Journal. ,vol. 80, pp. 516- 530 ,(2001) , 10.1016/S0006-3495(01)76034-1
MICHAEL JENKINS, RYAN S. WADE, YUANNA CHENG, ANDREW M. ROLLINS, IGOR R. EFIMOV, Optical coherence tomography imaging of the purkinje network. Journal of Cardiovascular Electrophysiology. ,vol. 16, pp. 559- 560 ,(2005) , 10.1046/J.1540-8167.2005.30621.X