PMUT: a web-based tool for the annotation of pathological mutations on proteins

作者: C. Ferrer-Costa , J. L. Gelpi , L. Zamakola , I. Parraga , X. de la Cruz

DOI: 10.1093/BIOINFORMATICS/BTI486

关键词:

摘要: … hot spot profiles for all non-redundant PDB structures are also accessible from the PMUT server. … In this paper we present the PMUT server, which implements our predictive models and …

参考文章(13)
Burkhard Rost, Chris Sander, Prediction of Protein Secondary Structure at Better than 70% Accuracy Journal of Molecular Biology. ,vol. 232, pp. 584- 599 ,(1993) , 10.1006/JMBI.1993.1413
Carles Ferrer-Costa, Modesto Orozco, Xavier de la Cruz, Use of bioinformatics tools for the annotation of disease-associated mutations in animal models. Proteins. ,vol. 61, pp. 878- 887 ,(2005) , 10.1002/PROT.20664
Roger Sayle, James Milner-White, RASMOL: biomolecular graphics for all Trends in Biochemical Sciences. ,vol. 20, pp. 374- 376 ,(1995) , 10.1016/S0968-0004(00)89080-5
Carles Ferrer-Costa, Modesto Orozco, Xavier de la Cruz, Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties. Journal of Molecular Biology. ,vol. 315, pp. 771- 786 ,(2002) , 10.1006/JMBI.2001.5255
Zhen Wang, John Moult, SNPs, protein structure, and disease Human Mutation. ,vol. 17, pp. 263- 270 ,(2001) , 10.1002/HUMU.22
C. Ferrer-Costa, M. Orozco, X. de la Cruz, Sequence-based prediction of pathological mutations Proteins: Structure, Function, and Bioinformatics. ,vol. 57, pp. 811- 819 ,(2004) , 10.1002/PROT.20252
Helen M Berman, Tammy Battistuz, Talapady N Bhat, Wolfgang F Bluhm, Philip E Bourne, Kyle Burkhardt, Zukang Feng, Gary L Gilliland, Lisa Iype, Shri Jain, Phoebe Fagan, Jessica Marvin, David Padilla, Veerasamy Ravichandran, Bohdan Schneider, Narmada Thanki, Helge Weissig, John Westbrook, Christine Zardecki, The Protein Data Bank Nucleic Acids Research. ,vol. 28, pp. 235- 242 ,(2000) , 10.1093/NAR/28.1.235
Pauline C Ng, Steven Henikoff, Accounting for Human Polymorphisms Predicted to Affect Protein Function Genome Research. ,vol. 12, pp. 436- 446 ,(2002) , 10.1101/GR.212802
Marco Punta, Penny C Coggill, Ruth Y Eberhardt, Jaina Mistry, John Tate, Chris Boursnell, Ningze Pang, Kristoffer Forslund, Goran Ceric, Jody Clements, Andreas Heger, Liisa Holm, Erik LL Sonnhammer, Sean R Eddy, Alex Bateman, Robert D Finn, None, The Pfam protein families database Nucleic Acids Research. ,vol. 30, pp. 276- 280 ,(2000) , 10.1093/NAR/GKR1065