Porphyromonas gingivalis virulence factors involved in subversion of leukocytes and microbial dysbiosis.

摘要: The oral bacterium Porphyromonas gingivalis has special nutrient requirements due to its asaccharolytic nature subsisting on small peptides cleaved from host proteins. Using proteases and other virulence factors, P. thrives as a component of polymicrobial community in nutritionally favorable inflammatory environments. In this regard, number strategies that subvert the immune response ways promote colonization facilitate outgrowth surrounding microbial community. focus review is discuss at molecular level how subverts leukocytes create environment for select bacteria that, turn, adversely affects periodontal tissues.