摘要: Since its original description by Pfeiffer in 1892 association with respiratory disease, Haemophilus influenzae has been found a number of clinical syndromes involving several organ systems. Encapsulated strains were recognized Pittman (1931) invasive disease and six serotypes (a-f) have described based on capsular antigen. Over 95% all associated producing the serotype b capsule, although due to other nonencapsulated described. Nonencapsulated are largely responsible for local mucosal tract contiguous structures such as otitis media, conjunctivitis, genitourinary infection, neonatal acquired from maternal genital tract. Infections H. perhaps most important bacterial infections childhood significant morbidity mortality.