Eligibility for Pre-exposure Prophylaxis According to Different Guidelines in a Cohort of HIV-Negative Men Who Have Sex with Men in Lisbon, Portugal

作者: Paula Meireles , Michael Plankey , Miguel Rocha , Jesus Rojas , João Brito

DOI: 10.1007/S13178-019-00426-9

关键词:

摘要: Defining eligibility for preexposure prophylaxis (PrEP) is key to measuring the degree of PrEP implementation. While clinical exclusion criteria are identical across different guidelines, definitions substantial HIV risk not. In this study, we aimed estimate proportion men who have sex with (MSM) being tested at a community-based voluntary human immunodeficiency virus (HIV) counseling and testing center in Lisbon that would be eligible according guidelines from World Health Organization (WHO), US Public Service Centers Disease Control Prevention (US-CDC), European AIDS Clinical Society (EACS), Portuguese National (PNHS). We used baseline data 3392 HIV-negative MSM valid information on enrolled Cohort MSM—an observational study designed as an open prospective, noninterval cohort—between March 2014 2018. At baseline, was 67.7% US-CDC, 60.6% PNHS 58.9% WHO, 46.5% EACS guidelines. The most frequently met were those related condomless anal intercourse. conclusion, same population, differed by guideline, ranging 67.7%, though if they all seem include well-known predictors seroconversion. These results show both allocation resources approaches individual prediction highly dependent chosen guideline. Moving focus assessing whether suitable option given moment his life might help overcome limitations create more equitable access.

参考文章(27)
Sheena McCormack, David T Dunn, Monica Desai, David I Dolling, Mitzy Gafos, Richard Gilson, Ann K Sullivan, Amanda Clarke, Iain Reeves, Gabriel Schembri, Nicola Mackie, Christine Bowman, Charles J Lacey, Vanessa Apea, Michael Brady, Julie Fox, Stephen Taylor, Simone Antonucci, Saye H Khoo, James Rooney, Anthony Nardone, Martin Fisher, Alan McOwan, Andrew N Phillips, Anne M Johnson, Brian Gazzard, Owen N Gill, Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial The Lancet. ,vol. 387, pp. 53- 60 ,(2016) , 10.1016/S0140-6736(15)00056-2
C Carvalho, R Fuertes, R Lucas, A Martins, MJ Campos, L Mendão, AJ Schmidt, H Barros, HIV testing among Portuguese men who have sex with men--results from the European MSM Internet Survey (EMIS). Hiv Medicine. ,vol. 14, pp. 15- 18 ,(2013) , 10.1111/HIV.12058
Aliete Cunha-Oliveira, Ilda Cardoso, José Cunha-Oliveira, None, Pedro Moura Ferreira, Manuel Villaverde Cabral (ed.). Sofia Aboim, Duarte Vilar e Marta Maia (col.). 2010. Sexualidades em Portugal: Comportamentos e Riscos. Lisboa: Editorial Bizâncio. Interações: Sociedade e as novas modernidades. ,vol. 11, ,(2011)
Kenneth H Mayer, Sybil Hosek, Stephanie Cohen, Albert Liu, Jim Pickett, Mitchell Warren, Douglas Krakower, Robert Grant, Antiretroviral pre-exposure prophylaxis implementation in the United States: a work in progress Journal of the International AIDS Society. ,vol. 18, pp. 19980- 19980 ,(2015) , 10.7448/IAS.18.4.19980
Sarah E. Woolf, Stephen A. Maisto, Alcohol Use and Risk of HIV infection among Men Who Have Sex with Men AIDS and Behavior. ,vol. 13, pp. 757- 782 ,(2009) , 10.1007/S10461-007-9354-0
Donald M. Berwick, Disseminating Innovations in Health Care JAMA. ,vol. 289, pp. 1969- 1975 ,(2003) , 10.1001/JAMA.289.15.1969
Robert M Grant, Javier R Lama, Peter L Anderson, Vanessa McMahan, Albert Y Liu, Lorena Vargas, Pedro Goicochea, Martín Casapía, Juan Vicente Guanira-Carranza, Maria E Ramirez-Cardich, Orlando Montoya-Herrera, Telmo Fernández, Valdilea G Veloso, Susan P Buchbinder, Suwat Chariyalertsak, Mauro Schechter, Linda-Gail Bekker, Kenneth H Mayer, Esper Georges Kallás, K Rivet Amico, Kathleen Mulligan, Lane R Bushman, Robert J Hance, Carmela Ganoza, Patricia Defechereux, Brian Postle, Furong Wang, J Jeff McConnell, Jia-Hua Zheng, Jeanny Lee, James F Rooney, Howard S Jaffe, Ana I Martinez, David N Burns, David V Glidden, None, Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men The New England Journal of Medicine. ,vol. 363, pp. 2587- 2599 ,(2010) , 10.1056/NEJMOA1011205
P. Meireles, R. Lucas, A. Martins, A. C. Carvalho, R. Fuertes, J. Brito, M. J. Campos, L. Mendao, H. Barros, The Lisbon Cohort of men who have sex with men BMJ Open. ,vol. 5, pp. 007220- ,(2015) , 10.1136/BMJOPEN-2014-007220
Luís Miguel Rocha, Maria José Campos, João Brito, Ricardo Fuertes, Jesus Rojas, Nuno Pinto, Luís Mendão, Julio Esteves, Acceptability of PrEP among HIV negative Portuguese men who have sex with men that attended 2014 Lisbon pride fair Journal of the International AIDS Society. ,vol. 17, pp. 19734- 19734 ,(2014) , 10.7448/IAS.17.4.19734
Ulrich Marcus, , Ford Hickson, Peter Weatherburn, Axel J Schmidt, Prevalence of HIV among MSM in Europe: comparison of self-reported diagnoses from a large scale internet survey and existing national estimates BMC Public Health. ,vol. 12, pp. 978- 978 ,(2012) , 10.1186/1471-2458-12-978