Interassay Differences in Growth Hormone Measurement in Acromegaly
作者： J H Barth , J H Smith , P Clarkson
DOI: 10.1177/000456329703400204
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摘要: We measured plasma growth hormone concentrations by three different two-site immunometric assays (Pharmacia hGH RIA, IDS Gamma-BCT and Delfia 22 kDa hGH) to determine whether there are GH isoforms secreted acromegalic patients that under-recognized some assays. There was a fairly good agreement between with the giving lower results than Pharmacia IRMA. on stored samples from 24 proven acromegaly. consistent difference of approximately 20% mean value for each patient.
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sci-hub.se 参考文章(7)
W. H. DAUGHADAY, R. H. STARKEY, S. SALTMAN, J. R. GAVIN, B. MILLS-DUNLAP, E. HEATH-MONNIG, Characterization of serum growth hormone (GH) and insulin-like growth factor I in active acromegaly with minimal elevation of serum GH. The Journal of Clinical Endocrinology and Metabolism. ,vol. 65, pp. 617- 623 ,(1987) , 10.1210/JCEM-65-4-617
J H Barth, J H Smith, P Clarkson, Wide diversity in measurements of growth hormone after stimulation tests in short children are due to assay variability Annals of Clinical Biochemistry. ,vol. 32, pp. 369- 372 ,(1995) , 10.1177/000456329503200403
T Yoshida, A Shimatsu, N Sakane, N Hizuka, R Horikawa, T Tanaka, Growth hormone (GH) secretory dynamics in a case of acromegalic gigantism associated with hyperprolactinemia: nonpulsatile secretion of GH may induce elevated insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 levels. The Journal of Clinical Endocrinology and Metabolism. ,vol. 81, pp. 310- 313 ,(1996) , 10.1210/JCEM.81.1.8550769
G. BAUMANN, Growth hormone binding proteins and various forms of growth hormone: implications for measurements. Acta Paediatrica. ,vol. 370, pp. 72- 80 ,(1990) , 10.1111/J.1651-2227.1990.TB11677.X
CARMEN CAMPINO, SZECOWKA, SZECOWKA, HAROLD SZECOWKA, SERÓN-FERRÉ SERON-FERRE, Certain Large Forms of Circulating Immunoreactive Human Growth Hormone Are in Fact Immunoglobulins The Journal of Clinical Endocrinology and Metabolism. ,vol. 70, pp. 601- 605 ,(1990) , 10.1210/JCEM-70-3-601
Yutaka Takahashi, Hidesuke Kaji, Yasuhiko Okimura, Katsumi Goji, Hiromi Abe, Kazuo Chihara, Short stature caused by a mutant growth hormone The New England Journal of Medicine. ,vol. 334, pp. 432- 436 ,(1996) , 10.1056/NEJM199602153340704
Steffi Brockmeier, M. Buchfelder, E. Adams, W. Schott, R. Fahlbusch, Acromegaly with 'normal' serum growth hormone levels. Clinical features, diagnosis and results of transsphenoidal microsurgery. Hormone and Metabolic Research. ,vol. 24, pp. 392- 396 ,(1992) , 10.1055/S-2007-1003342