Metformina: stary lek w nowej aplikacji

摘要: Metformin is a biguanide derivative that was synthesized in the 20's of last century. The main mechanism action ability to inhibit hepatic gluconeogenesis and trigger glucose uptake skeletal muscles. not only an antihyperglycaemic drug but also has protective effects on endothelium cells. In decade, many publications displayed metformin can reduce risk cancer diabetic patients demonstrated effect against certain types cancer. this review article, we discuss known mechanisms anticancer its beneficial role as vascular agent.