[15] Thermodynamic parameters from hydrogen exchange measurements

作者: Yawen Bai , Joan J. Englander , Leland Mayne , John S. Milne , S.Walter Englander

DOI: 10.1016/0076-6879(95)59051-X

关键词:

摘要: Just as exchangeable hydrogens that are controlled by global unfolding can be used to measure thermodynamic parameters at a level, exposed exchange local reactions may obtain locally resolved energy parameters. Results with the hemoglobin system demonstrate ability of HX methods locate functionally important changes in protein and energetic contribution each. These results offer promise measurements delineate, terms definable bonds their energies interactions, network interactions Hb other proteins use produce various functions.

参考文章(18)
R.K. Liem, D.B. Calhoun, J.J. Englander, S.W. Englander, A high energy structure change in hemoglobin studied by difference hydrogen exchange. Journal of Biological Chemistry. ,vol. 255, pp. 10687- 10694 ,(1980) , 10.1016/S0021-9258(19)70362-7
M. Guéron, J.-L. Leroy, Base-Pair Opening in Double-Stranded Nucleic Acids Nucleic Acids and Molecular Biology. pp. 1- 22 ,(1992) , 10.1007/978-3-642-77356-3_1
Aase Hvidt, Sigurd O. Nielsen, Hydrogen exchange in proteins. Advances in Protein Chemistry. ,vol. 21, pp. 287- 386 ,(1966) , 10.1016/S0065-3233(08)60129-1
S. Walter Englander, Catherine Mauel, Hydrogen Exchange Studies of Respiratory Proteins II. DETECTION OF DISCRETE, LIGAND-INDUCED CHANGES IN HEMOGLOBIN Journal of Biological Chemistry. ,vol. 247, pp. 2387- 2394 ,(1972) , 10.1016/S0021-9258(19)45441-0
E.L. Malin, S.W. Englander, The slowest allosterically responsive hydrogens in hemoglobin. Completion of the hydrogen exchange survey. Journal of Biological Chemistry. ,vol. 255, pp. 10695- 10701 ,(1980) , 10.1016/S0021-9258(19)70363-9
C. Woodward, I. Simon, E. T�chsen, Hydrogen exchange and the dynamic structure of proteins Molecular and Cellular Biochemistry. ,vol. 48, pp. 135- 160 ,(1982) , 10.1007/BF00421225
Yawen Bai, John S. Milne, Leland Mayne, S. Walter Englander, Protein stability parameters measured by hydrogen exchange Proteins. ,vol. 20, pp. 4- 14 ,(1994) , 10.1002/PROT.340200103
Norma M. Allewell, Hydrogen exchange studies of proteins: Recent advances in medium and high resolation methods Journal of Biochemical and Biophysical Methods. ,vol. 7, pp. 345- 357 ,(1983) , 10.1016/0165-022X(83)90060-X
M. F. PERUTZ, Stereochemistry of cooperative effects in haemoglobin. Nature. ,vol. 228, pp. 726- 734 ,(1970) , 10.1038/228726A0