Basic Concepts of Renal Physiology

作者: F. Lang , A. Busch

DOI: 10.1007/978-3-642-79565-7_2

关键词:

摘要: The most obvious function of the kidney is excretion xenobiotics, excessive electrolytes and trace elements, unnecessary and/or harmless metabolic products such as uric acid, urea ammonia. Through its excretory function, plays a pivotal role in regulation volume ion composition body fluids. For instance, it participates K+, Na+, CI–, HCO–, Ca2+, Mg2+ HPO2.– content thus influences intracellular fluid, extra cellular blood pressure, acid–base balance, mineral metabolism, etc. Accordingly, target various hormones. Furthermore, releases or activates hormones itself, erythropoietin, calcitriol [1,25–(OH)2D3], angiotensin, prostaglandins kinins. also carries out several important functions, gluconeogenesis, degradation fatty acids inactivation

参考文章(181)
Heini Murer, Gerhard Burckhardt, Membrane transport of anions across epithelia of mammalian small intestine and kidney proximal tubule. Reviews of Physiology Biochemistry and Pharmacology. ,vol. 96, pp. 1- 51 ,(1983) , 10.1007/BFB0031006
F. Lang, Renal handling of calcium and phosphate Journal of Molecular Medicine. ,vol. 58, pp. 985- 1003 ,(1980) , 10.1007/BF01476869
J. Eveloff, D. G. Warnock, K-Cl transport systems in rabbit renal basolateral membrane vesicles. American Journal of Physiology-renal Physiology. ,vol. 252, ,(1987) , 10.1152/AJPRENAL.1987.252.5.F883
D H Ellison, H Velázquez, F S Wright, Mechanisms of sodium, potassium and chloride transport by the renal distal tubule. Mineral and Electrolyte Metabolism. ,vol. 13, pp. 422- 432 ,(1987)
J. H. Dominguez, J. K. Rothrock, W. L. Macias, J. Price, Na+ electrochemical gradient and Na+-Ca2+ exchange in rat proximal tubule. American Journal of Physiology-renal Physiology. ,vol. 257, ,(1989) , 10.1152/AJPRENAL.1989.257.4.F531
A Jayakumar, L Cheng, C T Liang, B Sacktor, Sodium gradient-dependent calcium uptake in renal basolateral membrane vesicles. Effect of parathyroid hormone. Journal of Biological Chemistry. ,vol. 259, pp. 10827- 10833 ,(1984) , 10.1016/S0021-9258(18)90587-9
H. Oberleithner, G. Giebisch, F. Lang, W. Wang, Cellular mechanism of the furosemide sensitive transport system in the kidney Journal of Molecular Medicine. ,vol. 60, pp. 1173- 1179 ,(1982) , 10.1007/BF01716719
J. L. Garvin, M. B. Burg, M. A. Knepper, Active NH4+ absorption by the thick ascending limb American Journal of Physiology-renal Physiology. ,vol. 255, ,(1988) , 10.1152/AJPRENAL.1988.255.1.F57
R. Kinne, Properties of the Glucose Transport System in the Renal Brush Border Membrane Current topics in membranes and transport. ,vol. 8, pp. 209- 267 ,(1976) , 10.1016/S0070-2161(08)60198-7
B. C. Burckhardt, E. Frömter, Evidence for OH-/H+ permeation across the peritubular cell membrane of rat renal proximal tubule in HCO3(-)-free solutions. Pflügers Archiv: European Journal of Physiology. ,vol. 409, pp. 132- 137 ,(1987) , 10.1007/BF00584760