Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
作者： Giulia Palermo , Janice S. Chen , Clarisse G. Ricci , Ivan Rivalta , Martin Jinek
DOI: 10.1017/S0033583518000070
关键词:
摘要: … Here, molecular dynamics simulations performed using Anton-2 – a specialized … process of the endonuclease Cas9 toward DNA cleavage. Over the unbiased simulation, we observe …
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