Method of treatment of glutathione deficient mammals

作者: M. D. Robert H. Keller , David W. Kirchenbaum

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摘要: Glutathione (GSH) is a tripeptide of extreme importance as catalyst, reductan, and reactant. It can be depleted intracellulary either by forming direct complex with an electrophilic agent (accomplished investigationally agents such bromobenzene or diethyl maleate), way inhibition synthesis, subjecting cells to oxidant stress. Most cells, except for epithelia do not have transport capacity intact GSH. Non-epithelial must precursor substrates GSH synthesis salvage amino acids from circulating reuse in intracellular resynthesis. Dietary cysteine rate limiting substrate the glutathione also inhibits efflux. Although synthesized precursors virtually all liver main source plasma Protection support function paramount elevating levels. The disclosure unique combination nutritional supplements including n-acetyl cysteine, vitamin C, l-glucosamine, d-glucosamine, quercitin, sylimarin, Alpha lipoic acid high protein, low fat whey that are combined various bodily systems involved reutilization storage; intended elevate concentration mammalian cell.

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