Cardiac Muscle and the Troponins

作者: Elizabeth A. Hausner

DOI: 10.1007/978-3-319-15961-4_10

关键词:

摘要: The cardiac troponins (cTns) are structural proteins of the myocyte contractile apparatus. When measured in circulating blood, sensitive and specific indicators necrosis. elevation without necrosis remains controversial. Understanding now includes recognition role posttranslational modifications troponin T I modulation muscle contraction overall physiology. assays currently available for detection circulation immunologically based, using antibodies to a number epitopes T. Posttranslational modifications, proteolysis, single nucleotide polymorphisms may affect ability assay recognize on troponins. focus this chapter is an overview biology cTns, their contraction, with commercially assays.

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