Expanded Followup of Intravesical Oxybutynin Chloride Use in Children with Neurogenic Bladder

作者: Robert Kaplinsky , Saul Greenfield , Julian Wan , Margaret Fera

DOI: 10.1016/S0022-5347(01)65806-3

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摘要: AbstractPurpose: We evaluated the long-term results of intravesical oxybutynin chloride use in children with neurogenic bladders who could not tolerate or whose conditions were refractory to oral therapy.Materials and Methods: reviewed our experience 28 (myelomeningocele 27 imperforate anus 1) presented urinary incontinence and/or elevated bladder pressures intermittent catheterization anticholinergic medication. Intravesical was administered each child by instillation 5 mg. crushed 10 cc sterile saline 2 times daily during catheterization.Results: Seven patients (25 percent) secondary side effects. The remaining 21 have been followed on for a mean 35 months (range 3 67). Of these 12 (57 became completely dry day night, (24 achieved daytime continence between catheterizatio...

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