AMPK in the central nervous system: physiological roles and pathological implications
作者： Marco Segatto , Pamela Rosso , Marco Fioramonti , Anna Fracassi , Martina Marangoni
DOI: 10.2147/RRB.S90858
关键词:
摘要: AMP-activated protein kinase (AMPK) is considered the master metabolic regulator in all eukaryotes, as it maintains cellular energy homeostasis a variety of tissues, including brain. In humans, alterations AMPK activity can lead to wide spectrum disorders. The relevance this pathogenesis diabetes and syndrome now well established. On contrary, correlations between brain physiopathology are still poorly characterized. aim review summarize discuss current knowledge about prospective involvement onset progression different neurological diseases.
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