SOCS proteins, cytokine signalling and immune regulation

作者: Akihiko Yoshimura , Tetsuji Naka , Masato Kubo

DOI: 10.1038/NRI2093

关键词:

摘要: … Evidence is also emerging of the involvement of SOCS proteins in diseases of the immune … role in immunity, and propose a cohesive model of how cytokine signalling regulates immune-…

参考文章(112)
Lawrence O Flowers, Prem S Subramaniam, Howard M Johnson, A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells Oncogene. ,vol. 24, pp. 2114- 2120 ,(2005) , 10.1038/SJ.ONC.1208437
Atul K. Bhan, Emiko Mizoguthi, R. Neal Smith, Atsushi Mizoguchi, Colitis in transgenic and knockout animals as models of human inflammatory bowel disease. Immunological Reviews. ,vol. 169, pp. 195- 207 ,(1999) , 10.1111/J.1600-065X.1999.TB01316.X
Toshitaka Yajima, Hideo Yasukawa, Eun-Seok Jeon, Dingding Xiong, Andrea Dorner, Mitsuo Iwatate, Miwako Nara, Hanbing Zhou, Daphne Summers-Torres, Masahiko Hoshijima, Kenneth R. Chien, Akihiko Yoshimura, Kirk U. Knowlton, Innate Defense Mechanism Against Virus Infection Within the Cardiac Myocyte Requiring gp130-STAT3 Signaling Circulation. ,vol. 114, pp. 2364- 2373 ,(2006) , 10.1161/CIRCULATIONAHA.106.642454
G. M. Davey, W. R. Heath, R. Starr, SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation. Tissue Antigens. ,vol. 67, pp. 1- 9 ,(2006) , 10.1111/J.1399-0039.2005.00532.X
Koh Yamamoto, Mitsuko Yamaguchi, Nobuyuki Miyasaka, Osamu Miura, SOCS-3 inhibits IL-12-induced STAT4 activation by binding through its SH2 domain to the STAT4 docking site in the IL-12 receptor β2 subunit Biochemical and Biophysical Research Communications. ,vol. 310, pp. 1188- 1193 ,(2003) , 10.1016/J.BBRC.2003.09.140
Yun He, Wei Zhang, Rong Zhang, Haifeng Zhang, Wang Min, SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. Journal of Biological Chemistry. ,vol. 281, pp. 5559- 5566 ,(2006) , 10.1074/JBC.M512338200
Pooran Qasimi, Andrew Ming-Lum, Ali Ghanipour, Christopher J. Ong, Michael E. Cox, James Ihle, Nicolas Cacalano, Akihiko Yoshimura, Alice L-F. Mui, Divergent Mechanisms Utilized by SOCS3 to Mediate Interleukin-10 Inhibition of Tumor Necrosis Factor α and Nitric Oxide Production by Macrophages Journal of Biological Chemistry. ,vol. 281, pp. 6316- 6324 ,(2006) , 10.1074/JBC.M508608200
Ruslan Medzhitov, Seth Rakoff-Nahoum, Liming Hao, Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis Immunity. ,vol. 25, pp. 319- 329 ,(2006) , 10.1016/J.IMMUNI.2006.06.010
Toshikatsu Hanada, Hiroki Yoshida, Seiya Kato, Kentaro Tanaka, Kohsuke Masutani, Jun Tsukada, Yoshio Nomura, Hiromitsu Mimata, Masato Kubo, Akihiko Yoshimura, Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity Immunity. ,vol. 19, pp. 437- 450 ,(2003) , 10.1016/S1074-7613(03)00240-1
Lynn M. Williams, Usha Sarma, Kate Willets, Tim Smallie, Fionula Brennan, Brian M. J. Foxwell, Expression of Constitutively Active STAT3 Can Replicate the Cytokine-suppressive Activity of Interleukin-10 in Human Primary Macrophages Journal of Biological Chemistry. ,vol. 282, pp. 6965- 6975 ,(2007) , 10.1074/JBC.M609101200