A pilot study of food supplementation to improve adherence to antiretroviral therapy among food-insecure adults in Lusaka, Zambia
作者： Ronald A Cantrell , Moses Sinkala , Karen Megazinni , Sibi Lawson-Marriott , Sierra Washington
DOI: 10.1097/QAI.0B013E31818455D2
关键词:
摘要: BACKGROUND: The provision of food supplementation to food-insecure patients initiating antiretroviral therapy (ART) may improve adherence medications. METHODS: A home-based support program at 8 government clinics assessed for insecurity. Four provided and 4 acted as controls. analysis compared (assessed by medication possession ratio) CD4 weight gain outcomes among enrolled the with those control clinics. RESULTS: Between May 1 2004 March 31 2005 636 food- insecure adults were enrolled. Food was associated better therapy. Two hundred fifty-eight 366 (70%) in group achieved a ratio 95% or greater versus 79 166 (48%) controls (relative risk = 1.5; confidence interval: 1.2 1.8). This finding unchanged after adjustment sex age baseline count World Health Organization stage hemoglobin. We did not observe significant effect on cell response. CONCLUSIONS: suggests that providing ART is feasible medication. large randomized study clinical benefits urgently needed inform international policy.
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