Drug Transport in the Placenta

Eric M. van der Aa, Jenny H.J. Copius Peereboom-Stegeman, Jan Noordhoek, Frank W.J. Gribnau, Frans G.M. Russel, Mechanisms of drug transfer across the human placenta. Pharmacy World & Science. ,vol. 20, pp. 139- 148 ,(1998) , 10.1023/A:1008656928861

B J Simon, P Kulanthaivel, G Burckhardt, S Ramamoorthy, F H Leibach, V Ganapathy, Characterization of an ATP-driven H+ pump in human placental brush-border membrane vesicles. Biochemical Journal. ,vol. 287, pp. 423- 430 ,(1992) , 10.1042/BJ2870423

Pedro Cano-Soldado, Marçal Pastor-Anglada, Transporters That Translocate Nucleosides and Structural Similar Drugs: Structural Requirements for Substrate Recognition Medicinal Research Reviews. ,vol. 32, pp. 428- 457 ,(2012) , 10.1002/MED.20221

Henriette E.U. Meyer zu Schwabedissen, Markus Grube, Björn Heydrich, Knud Linnemann, Christoph Fusch, Heyo K. Kroemer, Gabriele Jedlitschky, Expression, Localization, and Function of MRP5 (ABCC5), a Transporter for Cyclic Nucleotides, in Human Placenta and Cultured Human Trophoblasts: Effects of Gestational Age and Cellular Differentiation American Journal of Pathology. ,vol. 166, pp. 39- 48 ,(2005) , 10.1016/S0002-9440(10)62230-4

D F Balkovetz, F H Leibach, V B Mahesh, V Ganapathy, A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles. Journal of Biological Chemistry. ,vol. 263, pp. 13823- 13830 ,(1988) , 10.1016/S0021-9258(18)68318-8

David T. Thwaites, Catriona M. H. Anderson, H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine Experimental Physiology. ,vol. 92, pp. 603- 619 ,(2007) , 10.1113/EXPPHYSIOL.2005.029959

V Ganapathy, M E Ganapathy, C N Nair, V B Mahesh, F H Leibach, Evidence for an organic cation-proton antiport system in brush-border membranes isolated from the human term placenta. Journal of Biological Chemistry. ,vol. 263, pp. 4561- 4568 ,(1988) , 10.1016/S0021-9258(18)68819-2

Joan Keegan, Mehdi Parva, Mark Finnegan, Andrew Gerson, Michael Belden, Addiction in Pregnancy Journal of Addictive Diseases. ,vol. 29, pp. 175- 191 ,(2010) , 10.1080/10550881003684723

Mark GRIFFITHS, Y. M. Sylvia YAO, Fatima ABIDI, E. V. Simon PHILLIPS, E. Carol CASS, D. James YOUNG, A. Stephen BALDWIN, Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochemical Journal. ,vol. 328, pp. 739- 743 ,(1997) , 10.1042/BJ3280739

Eva Innala, Lucia Mincheva-Nilsson, Ann-Christin Stenqvist, Ting Chen, Malin Hedlund, Tanya Dimova, Olga Nagaeva, Lennart Kjellberg, An efficient optimized method for isolation of villous trophoblast cells from human early pregnancy placenta suitable for functional and molecular studies. American Journal of Reproductive Immunology. ,vol. 60, pp. 33- 42 ,(2008) , 10.1111/J.1600-0897.2008.00588.X