作者: Jeffrey C. Leung , Gregory L. Ruff , Martin W. King , Philip P. Dattilo
DOI: 10.1533/9781845694104.7.395
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摘要: ABSTRACT Surgical sutures are the most frequently used biomaterials for wound closure and tissue approximation. However, they rely on surgeon's ability to tie secured knots, which is a challenging time consuming process. Improper tying handling can result in knot breakage or slippage, potentially dehiscence. Further, impedes healing, constricts blood flow, distorts tissue, increases scar formation. To alleviate these problems, attempts have been made design self-anchoring sutures. Recently, novel knotless suture has developed ( Figure 1 ) bi-directional barbs introduced into an absorbable monofilament using micro-machining techniques. This paper describes analytical characterization of barb geometry, biomechanical performance suture, including vitro vivo testing. The former employs specialized microscopy image analysis latter entails tensile strength testing apposition tissues with variety stitch techniques, comparison commercially available These results will form basis further research barb/tissue interactions optimization geometry specific surgical applications.