Therapeutic results with Cerebrolysin in the treatment of dementia.

摘要: BACKGROUND In the present study patients suffering from dementia were treated with an infusion therapy using neurotrophic drug Cerebrolysin. The effectiveness of was examined under conditions daily clinical practice. METHODS 645 Patients 30 ml Cerebrolysin daily. average period treatment 17.8 days. Prior to diagnosed according DSM-III-R. addition a differential diagnostic examination Hachinski Ischemic Score performed. Clinical symptoms and Global Impression (CGI) determined before after therapy. RESULTS led significant (p < 0.001) improvement in memory for 62% patients. 65% showed concentration, 50% mood fatigue, 47% improved vertigo. An impression observed approximately 80% significantly larger 0.05) younger, less afflicted than older, more seriously ill unusual good tolerance especially noteworthy. CONCLUSIONS confirms results earlier studies Alzheimer vascular which similar responder rates observed. dependence therapeutic success on length severity illness that timely pharmacological intervention leads best results.