Estrone sulfate: a potential source of estradiol in human breast cancer tissues.
作者： Steven J. Santner , Donald Leszczynski , Carol Wright , Andrea Manni , Peter D. Feil
DOI: 10.1007/BF01886734
关键词:
摘要: Local formation of estradiol in human breast tumors could provide a more important source estrogen than is delivered from plasma. Prior studies have suggested that estrone primarily synthesized sulfate. The enzyme 17β-hydroxysteroid dehydrogenase (HSD) would be required to convert estradiol.
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