Gastrointestinal and General Abdominal Symptoms

摘要: Gastrointestinal manifestations of metabolic disorders may occur as part a systemic disorder intermediary metabolism in which other symptoms predominate or the major exclusive symptoms. Vomiting occurs frequently and is typical organic acidurias, hyperammonemic syndromes, fatty acid oxidation defects. Pain not uncommon but this category usually considered until several episodes abdominal pain have occurred without an obvious explanation. It often intense lead to surgical exploration. In porphyrias familial fever central clinical feature. Pancreatitis with many lipid disorders, defects oxidative phosphorylation. Diarrhea failure thrive, together malabsorption, are very common can be due digestive enzymes, especially disaccharidases, carrier proteins, congenital glycosylation, also mitochondrial dysfunction. Finally, ascites lysosomal disorders.