Chemical coding of enteric neurons.

作者: M. Costa , J.B. Furness , I.L. Gibbins

DOI: 10.1016/S0079-6123(08)60241-1

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摘要: Publisher Summary This chapter describes earlier observations that lead to the view there is a precise multiple neurochemical coding of subpopulations enteric neurons, which form intricate neuronal circuits control intestinal functions. In mammalian nervous system, are as many neurons in spinal cord, and numerous different characterized by substances they contain, their shapes, projections. Most gastrointestinal functions—that is, motility with its vast repertoire behavior, blood flow, secretion absorption water electrolytes—are known be controlled or influenced autonomic nerves. The discovery coexistence chemical messengers prompted systematic immunohistochemical investigation patterns neurons. discusses methods for simultaneous localization two antigens problems encountered demonstrates some applications studies messengers. principle organization system provides an extremely valuable framework working out circuitry assists identifying possible roles individual proposes reevaluation terminology notation encompass realization every neuron has each may transmit messages.

参考文章(75)
S Leander, R Håkanson, F Sundler, Peptidergic nervous systems in the gut. Clinics in gastroenterology. ,vol. 9, pp. 517- 543 ,(1980) , 10.1016/S0300-5089(21)00469-7
J. B. Furness, M. Costa, Identification of Gastrointestinal Neurotransmitters Mediators and Drugs in Gastrointestinal Motility I. pp. 383- 462 ,(1982) , 10.1007/978-3-642-68437-1_11
J. B. Furness, M. Costa, The adrenergic innervation of the gastrointestinal tract. Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie. ,vol. 69, pp. 2- 51 ,(1974) , 10.1007/3-540-06498-2_1
S.G. Griffith, G. Burnstock, Serotoninergic neurons in human fetal intestine: an immunohistochemical study Gastroenterology. ,vol. 85, pp. 929- 937 ,(1983) , 10.1016/0016-5085(83)90446-8
G. M. Lees, H. W. Kosterlitz, PHARMACOLOGICAL ANALYSIS OF INTRINSIC INTESTINAL REFLEXES. Pharmacological Reviews. ,vol. 16, pp. 301- 339 ,(1964)
Rolf Håkanson, Frank Sundler, E. Ekblad, R. Ekman, GRP neurones in the rat small intestine issue long anal projections Regulatory Peptides. ,vol. 9, pp. 279- 287 ,(1984) , 10.1016/0167-0115(84)90080-6