Miocene DNA sequences — a dream come true?

作者: Svante Pääbo , Allan C Wilson

DOI: 10.1016/0960-9822(91)90125-G

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摘要: The advent of the polyrnerase chain reaction (PCR) is transforming many aspects molecular biology. An example this field ‘molecular archaeology’ retrieval DNA sequences from ancient tissues which owes its very existence to technique [ 11. ability PCR amplify a few intact molecules that are extracted old has for first time ‘made it possible go back in and study sequences. Indeed, can even recreate longer short fragments test tube [2]. Thus, we now dream :about catching evolution red-handed. So far, dlreams about sort travel have come true only trips into past. Until recently, oldest determined were 40000-year-old mammoth (RG. Higuchi, unpublished results).

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